When the heart is under stress, such as in cases of heart failure, the production of BNP increases. BNP acts to promote the excretion of salt and water by the kidneys, which helps to reduce the volume of blood in the circulatory system and alleviate the workload on the heart.
It levels can be measured through a blood test, which is often used to help diagnose heart failure, assess the severity of the condition, and guide treatment. In general, higher levels of BNP are associated with a higher risk of heart failure and worse outcomes.
It testing is also used in other clinical settings, such as in the evaluation of shortness of breath, pulmonary hypertension, and other cardiovascular conditions. However,
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It levels can also be elevated in non-cardiac conditions such as chronic kidney disease, liver disease, and sepsis, so the test must be interpreted in the context of the patient’s clinical history and other diagnostic tests.